Know your risk.

Individuals of Ashkenazi Jewish descent have a one-in-forty risk of inheriting a BRCA gene mutation, increasing their risk of developing hereditary breast (male or female), ovarian and prostate cancer.

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Watch this PSA from the BFOR Study to learn how genetic testing can save lives.


by our roots

American Jews of eastern and central European descent (Ashkenazi) have a one in forty risk of having a mutation in their BRCA1 or BRCA2 gene that puts them at much higher risk than the general population of developing ovarian cancer, breast cancer (male or female) and prostate cancer.

What Is BRCA?


by knowledge

Both men and women are at risk of developing hereditary cancer and can pass on a BRCA 1 or 2 gene mutation. It’s important to know your family history and to speak with a genetic counselor. With knowledge of your risk, you can make informed decisions to protect you and your family’s health.

Read Stories


by resources

Oneinforty supports the community with an ambassador program and social media channels, offers educational symposia with expert oncologists and genetic counselors, physician education and emotional support through a cadre of mental health providers.


“I am Oneinforty” Stories

“It was a long journey and I didn’t come to my decision quickly. Having a mastectomy meant I could put my family history of breast cancer behind me, and I felt relief.”

Read Caitlin's Story

“A clinical breast exam does not appear on the to-do lists of many men. But it should…at least for one in every forty Ashkenazi Jews like me.”

Read Eric's Story

“While being aware of my BRCA1 positive status did not prevent me from being diagnosed it did allow me to avoid what almost certainly would have evolved into to advanced ovarian cancer.

Read Susan's Story

Next Symposium to be scheduled soon.

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Oneinforty was founded from personal experience.

In late 2016 at the age of forty-five, Lauren Corduck underwent genetic testing which found she had inherited the BRCA1 gene mutation from her father. Even though there was a family history of breast cancer and she was of Ashkenazi Jewish descent, Lauren had never been advised by a physician to seek genetic testing. Almost simultaneously to learning of her BRCA mutation, she was diagnosed with Stage 4 ovarian cancer. Lauren, who died in December of 2020, started Oneinforty in 2017, with the goal of helping other families avoid a similar experience.

Read more about Lauren’s journey. »

Read about Oneinforty in the news.

Boston Globe
Lauren Corduck, who founded Oneinforty to raise cancer risk awareness, dies at 49
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Local cancer survivor raises awareness of cancer gene mutation risk
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New York Times
Raising Awareness ofBRCA Mutations
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